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However, WADA has clarified that a specific class of diuretics called Carbonic Anhydrase Inhibitors, such as dorzolamide or brinzolamine, used in the eye in conjunction with a threshold substance does not require a TUE

Rats were acclimated for two weeks in a controlled setting with 12/12-hour light/dark cycles and a temperature of 25 2C and humidity

After consideration of these comments, and for the reasons stated above and in the proposed rule, we are finalizing as proposed the methodology for calculating the payment limit for a multiple source drug separately payable under Part B that has negative or zero manufacturer's ASP data reported for all NDCs associated with a billing and payment code for that drug at 414.904(i)

Chez les adultes en bonne sant, en revanche, les tudes sont rares, de courte dure et concernent un petit nombre de participants