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[7] [2] By 1986, the major review of the field by Graf and Kastin concluded that the various physiological functions of DSIP and its mechanism of action remain to be established. [2] That sentence was written four decades ago and has not been superseded

Notably, vascular remodeling may lead to the formation of leaky vessels, further contributing to epileptogenesis (71)

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6 Nanoparticles (NPs) have unique physicochemical properties such as small size and large surface area, which help them to cross the BBB and enable drug delivery to the lesion sites