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Among these, glutathione (GSH), a tripeptide antioxidant, has demonstrated versatile and potent ROS-scavenging properties ( Graphene oxide (GO) has emerged as a promising nanoplatform due to its high surface area, rich surface chemistry, and excellent biocompatibility when properly functionalized ( Precise localization of nanocarriers to the injury site is crucial for therapeutic efficacy

2026;6:1004136 DOI: Received: August 17, 2025 Accepted: November 24, 2025 Published: January 04, 2026 Academic Editor: Shile Huang, Louisiana State University Health Science Center, USA Neurodegenerative diseases, including Alzheimers, Parkinsons, Huntingtons, and Amyotrophic Lateral Sclerosis, are characterized by multifactorial pathologies that extend beyond neuronal loss to include neuroinflammation, oxidative stress, mitochondrial dysfunction, and glial dysregulation

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They have been mostly viewed as effectors of allergy and it has only been in the last two decades that they have gained significant attention for their involvement in a range of other physiological and pathological processes