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The LH can trigger the synthesis of androgens from theca cells that are converted to estrogen via the granulosa cells and a series of biochemical changes and aromatization

Peptides can have structures similar to those of certain hormones and signaling compounds in the body, allowing them to engage with and activate multiple receptors throughout the body, thereby influencing various bodily processes

While a single-donor model is more comparable to an in vivo situation then a multi-donor model, single-donor cardiac MTs might be more susceptible for bias due to genotype sensitivity than our multi-donor hepatic MTs that have the ability to even out these effects