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Oxidative stress and TNF-a induce histone Acetylation and NF-B/AP-1 activation in Alveolar epithelial cells: Potential mechanism In gene transcription in lung inflammation

At timepoint 360 min, we observed a pronounced drop in both fully labeled glucose and lactate in iPSCs, most likely reflecting depletion of the extracellular glucose supply (5 mM) in the medium, which may have contributed to the onset of gluconeogenesis, highlighting a metabolic adaptation in response to nutrient availability [67]

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