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Life Sci 194:8897 Wen SW, Liu S, Joseph K, Rouleau J, Allen A (2000) Patterns of infant mortality caused by major congenital anomalies

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Consistent with HeLa cell experiments, mitochondrial iron levels were significantly reduced in HMOX2 KO C2C12 cells compared to WT C2C12 cells, and re-expressing HMOX2 WT in HMOX2 KO cells restored iron levels, but not in cells re-expressing the HMOX2 K68R mutant (Fig