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Notably, the type IIx/IIb cluster had a lower percentage of mitochondrial reads than the type IIx and type IIb clusters, indicating that these cells were not clustering together due to being lower quality (Extended Data Fig

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Interestingly, an oxyntomodulin multi-agonist was under investigation concurrently with the GLP1/glucagon multi-agonist

During treatment with trial product (any dose of trial medication administered within the previous 2 weeks (that is, any period of temporary treatment interruption with trial product was excluded))