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28 Excessive ROS production leads to an oxidative inactivation of anti-proteases, alveolar epithelium damage, increased neutrophil retention and increased expression of various inflammatory mediators in the pulmonary microcirculation, aggravating the development of COPD

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Considering their overexpression in cancers including liver and lung cancer, GLUT1 and YBX1 may be used as both biomarkers and therapeutic targets for the combination treatment

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