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Saeterdal I, Bjrheim J, Lislerud K, Gjertsen MK, Bukholm IK, Olsen OC, et al

10.1016/j.phrs.2020.105007 Pharmacol

Therefore, introducing drug development technologies, such as computer-aided drug design, high-throughput screening, systems modeling and simulation to obtain derivatives of AS-IV with increased bioavailability and conducting targeted validation or further adopting biocompatible drug carriers, such as nanoparticles, liposomes and micelles encapsulating AS-IV, may be required to achieve its efficient delivery