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Interestingly, for the first time, we report that PSPH amplifications in GBM dictate the expression of immune checkpoint galectin-1, supported by poor anti-PD1 immunotherapy responses and outcome in patients with GBM

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Bhui and co-authors explored that bromelain inhibits COX-2 expression by blocking the activation of MAPK-regulated NF-kappa B against skin tumor initiation triggering the mitochondrial death pathway (139)

A case for the evolution from commensalism to pathogenicity and possibly back again: lessons learned from the human-adapted neisseria species