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numerous randomizec controlled trials have investigated the role of omega-3 FA supplementation in the relief for dry eye. While many studies have shown a benefit in dry eye management,' a Cochrane systematic review on this topic included 4314 adult participants with dry eye of variable severities and etiologies, with up to 12 months of follow- up data from 34 randomized controlled trials.!" In evaluating these clinical data the comprehensive analysis reached the key conclusion that-when it comes to dry eye-the collective evidence for the benefit of omega-3 supplementation is uncertain