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ERK1/2 activation upregulates collagen gene expression and promotes cell proliferation critical for fibroblast proliferation, while p38 MAPK inhibition reduces inflammatory response

The protection effect can also be abolished by the expression of exogenous NMN and ectopic expression of NMN deamidase

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A little more than a decade ago, the utility began to develop what would eventually become the Sustainable Water Initiative for Tomorrow (SWIFT), an innovative managed aquifer recharge system that Hazen helped HRSD design