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Protect from Light: The refrigerator naturally keeps it dark, but its good practice to store it in its original box or another container to shield it from light whenever the door is opened

The conversion rate was calculated as follows: Results and discussion Sample preparation of the conversion SIDA method The sample preparation of the conversion SIDA method was developed and optimized aiming at achieving complete conversions of all native cobalamins into the cyano-form, a prerequisite for accurate quantification of total B12 as CNCbl

Weve found that the main compartment of the refrigerator provides a more stable temperature than the door, which fluctuates frequently

Although these studies report promising results regarding the sublingual route, it is important to note that almost all of them only include patients with mild, subclinical B12 deficiency, making it difficult to extrapolate their outcomes for patients with severe deficiency or malabsorptive states