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10.1136/gut.2010.228874 32 GuanZ.ChenJ.LiX.DongN

SHMT2, one of the key enzymes in serine metabolism, is upregulated in certain tumors (113117)

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In vivo pharmacokinetics, conducted in Sprague-Dawley rats, showed sustained PX plasma levels over two weeks, with a maximum plasma concentration of 19.06 4.73 ng/mL observed at 48 0.25 h