mrp1 glutathione sirt1

mrp1 glutathione sirt1 Molecular analysis of the massive GSH transport mechanism mediated by the human Multidrug Resistant Protein 1/ABCC1 Frontiers | Involvement of SIRT1-mediated

Name: mrp1 glutathione sirt1 Molecular analysis of the massive GSH transport mechanism mediated by the human Multidrug Resistant Protein 1/ABCC1 Frontiers | Involvement of SIRT1-mediated
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Frontiers Involvement of SIRT1 mediated aging in liver diseases Role of Glutathione in Cancer: From Mechanisms to Therapies Glutathione driven redox decisions in cell survival and death MRP1 modulators synergize with buthionine sulfoximine to exploit collateral sensitivity and selectively kill MRP1 expressing cancer cells ScienceDirect

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Description

Public Health 20 , 6721 (2023)

Peptides are biological signaling molecules that support cellular communication involved in repair and tissue maintenance

Reduced GSH and oxidized GSSG are well-known substrates of MRP-1 and are transported or undergo co-efflux in various physiological processes and pharmacological conditions 3

In addition, sex steroid hormones have been implicated in the modulation of genome stability in endocrine-driven malignancies, including breast and prostate cancer [138]