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[DOI] [PubMed] [Google Scholar] Matsui H., Grubb B.R., Tarran R., Randell S.H., Gatzy J.T., Davis C.W., Boucher R.C

The most cited clinical trial is the open-label MASLD pilot by Honda et al., in which 300 mg/day oral glutathione for 4 months reduced ALT and hepatic steatosis in 29 patients, but without histological or survival data and with no control arm ( The impact of glutathione supplementation on this cohort presents a complex picture that requires careful interpretation

These include scavenging FRs, breaking down peroxides, and interacting with pro-oxidant metal ions

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