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Description

Recent genetic mouse models in which TSPO had been deleted tissue specifically and globally have yielded conflicting results regarding steroidogenesis, ranging from no effect on steroidogenesis to severe compromise of ACTH-stimulated production of corticosterone (129131)

this condition is characterized by an inadequate response to exogenous gonadotropins or a low ovarian reserve, considering age, ovarian biomarkers (antral follicle count [AFC] and AMH), and the ovarian response in previous stimulation cycles, as defined by the Patient-Oriented Strategies Encompassing Individualized Oocyte Number (POSEIDON) classification [59]