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Mechanism by which caloric restriction improves insulin sensitivity in sedentary obese adults

The presence of tumor stem cells is directly correlated with chemotherapy resistance in HGSOC, and these cells can evade drug effects through multiple mechanisms ( In our comprehensive exploration of HGSOC drug resistance mechanisms, we identified a complex and diverse biological foundation involving abnormalities in multiple cellular signaling pathways and alterations in the tumor microenvironment

doi: 10.1021/acscentsci.9b01063

These activated subunits bind to flavocytochrome and induce the synthesis of radical species such as O 2 and OH [87]