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10.1016/j.micpath.2023.106159 47 HeZ.GuoJ.ZhangH.YuJ.ZhouY.WangY.et al (2023b)

JAK2 Variants Associated with Secondary-AML from MPN

However, efforts to demonstrate the clinical benefit of DUB inhibition have been hampered by the poor selectivity of early compounds, as well as a limited understanding of DUB biology, especially the scope of unique and shared substrates across the family of DUB enzymes

Coenzyme Q10 (CoQ10), also referred to as ubiquinone, primarily facilitates electron transfer from complexes I and II to complex III in the mitochondrial electron transport chain