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Validation strategies, split-sample testing, permutation analyses, and receiver operating characteristic (ROC) curves, have confirmed the discriminatory capacity of small metabolite panels (46 compounds), with many models reaching area under the curve (AUC) values greater than 0.85

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The study provides a new and ideal therapeutic option for diabetic fracture and other musculoskeletal diseases. The study employed the plant-based drug production platform that Daniell has developed over many years, which entails introducing a protein of interest into plant cells, prompting them to begin expressing that gene in their cells, eventually producing that protein in their leaves which can be harvested and used in an oral therapy

Frontiers in Immunology, 8