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The reference group received no intervention, and no improvement in health complaints was found

A randomized, controlled trial of oral intestinal sorbent AST-120 on renal function deterioration in patients with advanced renal dysfunction

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red and green filter photos indicate that the hyperpigmentation is below the level of the retinal pigmented epithelium, consistent with the previously noted reports of this hyperpigmentation being localized between Bruchs membrane and the retinal pigmented epithelium