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Carnitine forms a high-energy ester bond with long chain fatty acids by the action of carnitine palmitoyl transferase 1 (CPT-1), located in the inner aspect of the outer mitochondrial membrane, with the formation of acylcarnitines [3]

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Recent studies demonstrated that alterations in lipid metabolism, especially arachidonic acid metabolism like PGE2, 5-HPETE, TXA2, and TXB2, influenced the inflammatory response in post-stroke mice, and MALDI-imaging was then used to identify the expression of lipid peaks in the brain (Supplementary Fig