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References 1.Harris AL

NMN treatment has also demonstrated similar efficacy in a mouse model of myocardial fibrosis, reducing cardiac ejection fraction and aggravating myocardial fibrosis by upregulating cardiac cell SIRT6 protein expression (Yu et al., 2020)

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The cell suspension was lysed on ice by sonication and the lysate was centrifuged at 17,000 g for 30 min at 4 C to remove the insoluble cellular debris