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doi: 10.1093/carcin/14.2.183

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This is the first time the agency has taken steps to remove a currently marketed opioid pain medication from sale due to the public health consequences of abuse...[FDA Commissioner Scott Gottlieb, M.D.]: "We are facing an opioid epidemic a public health crisis, and we must take all necessary steps to reduce the scope of opioid misuse and abuse

The increased glutathione redox status could be a compensatory mechanism in response to the increased oxidative burden due to anemia and obesity