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Side Effects & Safety No lethal dose found -- toxicology studies couldn't establish an LD50 (Sikiric et al., 2006) No organ toxicity in chronic dosing No hormonal effects -- doesn't affect testosterone, estrogen, cortisol, or GH Mild nausea -- mostly with oral dosing Brief lightheadedness -- occasionally after injection Injection site redness -- standard for SC peptides Angiogenesis concern -- promotes new blood vessel growth, which raises a theoretical question about existing tumors

In order to reduce the risk of NTDs, there is wide agreement that all persons capable of becoming pregnant take supplemental folic acid

We need selenium to power glutathione peroxidase (GPX), the enzyme that removes free radicals inside the cell