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Dec 1 2019;259:302-313

Tirona RG, Kim RB

Intracellular Ca 2 + activates calpain and CDK5 pathway involved in tau phosphorylation

The combined administration of PQ with maneb or its closely related chemical, mancozeb, has also been applied to study the effects of PQ on the nigrostriatal dopamine system and was found to reproduce PD symptoms better than PQ alone (Thiruchelvam et al., 2000a,b)