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Such an imbalance is responsible for severe damage to essential biomolecules, such as lipids (lipid peroxidation), proteins (oxidation and inactivation), and DNA (strand breakage and mutations), which is associated with the pathogenesis of numerous diseases, including cancer, neurodegenerative diseases, cardiovascular diseases, and the aging process [28]

J Integr Plant Biol 63:5378

Gprc5a deletion enhances the transformed phenotype in normal and malignant lung epithelial cells by eliciting persistent Stat3 signaling induced by autocrine leukemia inhibitory factor