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Metal ions are deeply involved in cell metabolism Metal ions play a vital role in cell metabolism, as they participate in various ionic states throughout processes such as absorption, distribution, storage, and elimination, at both the cellular and systemic levels in multicellular organisms

With regard to dietary supplements , patients should be aware of the following: Herbal supplements with hypoglycaemic properties such as berberine, bitter melon, or fenugreek may enhance blood glucose-lowering effects and increase hypoglycaemia risk, particularly when used alongside insulin or sulfonylureas

Jiahui L, Guowei W, SHA C, et al

As mentioned in this review, the application of nanomaterials opens a breakthrough for the clinical application of drugs targeting mitochondria