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doi: 10.1111/acel.12062 134 AlbrightJWAlbrightJF

compared 2.51% arbutin with a placebo in 50 melasma patients of Polish origin

Concurrently, lactate induces polarization of helper T (Th) and CD4+ T cells, fostering an immunosuppressive environment that suppresses Th1 subsets critical for antitumor activity (17)