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Description

The advantage of this hydrophilic and permanently charged group is solubility, which not only enables bioconjugation with lipophilic glucocorticoid derivatives but also facilitates ADC purification with less than 0.10% residual linkers in ADC

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Desmots F, Rissel M, Gilot D, Lagadic-Gossmann D, Morel F, Guguen-Guillouzo C, Guillouzo A et al

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Unveiling tumor immune evasion mechanisms: abnormal expression of transporters on immune cells in the tumor microenvironment

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Cell 185 , 513529.e21 (2022)

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