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In the feet, this can lead to: Tingling or pins and needles sensations Numbness or reduced ability to feel pain, heat, or cold Burning or shooting pain, especially at night Muscle weakness or instability when walking Neuropathy often develops gradually, and without early treatment, it can worsen over timeincreasing your risk of injuries, ulcers, and infections

Cisplatin, a widely used chemotherapeutic, has been studied extensively for interactions with analgesics including paracetamol

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Wang M , Ramchandren R, Chen R, Karlin L, Chong G, Jurczak W, Wu KL, Bishton M, Collins GP, Eliadis P, Peyrade F, Lee Y, Eckert K, Neuenburg JK, Tam CS Concurrent ibrutinib plus venetoclax in relapsed/refractory mantle cell lymphoma: the safety run-in of the phase 3 SYMPATICO study