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Macrophage polarization states in the tumor microenvironment

5.3 Patient-centred decision making Patient-centred decision making is a key translation perspective in the integration of natural supplements to breast cancer therapy, simultaneously focusing on individualized patient care, informed consent, shared and rational decision making that aligns therapeutic options with patients values and preferences and potential of clinical context (235)

And two of the most powerful tools in that system are glutathione and turmeric-derived curcuminoids

Ubiquitin- and ATP-independent degradation can be carried out by the free 20S proteasome complex