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Description

Due to their hydrophobicity, dietary fats, mostly composed of long-chain fatty acids, are packaged as triglycerides (TGs) into chylomicrons in intestinal enterocytes and distributed to nonhepatic tissues (e.g., adipose depots) through the lymphatic system, thereby bypassing metabolism in the liver 5

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The IP 3 inhibitor 2-APB (2-aminoethoxydiphenyl borane) decreases T-cellactivation- induced Ca 2+ and NO production, and NO treatment of T lymphocytes leads to an increase in mitochondrial and cytoplasmic Ca 2+ levels