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When we measured the levels of various metabolites, we found that patients with OC could be divided into two groups: high and low metabolite levels, with the former having more advanced-stage ovarian tumors

10.1038/s41398-020-01135-3 148

These events induce proteotoxic stress, ultimately leading to cell death

Conclusion: Results demonstrate a low prevalence (2.4%) of CT head abnormality in cirrhotic patients presenting with hepatic encephalopathy and a low yield of routine CT head use in the absence of trauma or focal neurological deficit