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(1992) Contribution of five amino acid residues in the glutathione-binding site to the function of human glutathione transferase Pl-1, Biochem

Adal and Wiener (2020) reported that individuals who suffer from chronic metal toxicity are more likely to display noticeable signs and symptoms of both their central and peripheral nervous systems

By counteracting mitochondrial generation of ROS GPx4 appears to protect neuronal cells from oxidative modification of AIF, which prevents AIF cleavage and release into the cytosol (Seiler et al., 2008)