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In this review, we provide a succinct overview focusing on the regulatory role of succinate in innate immune cells, highlighting involved mechanisms and research gaps that represent promising targets for future study

We herein propose reasonable hypotheses potentially counting for the contradictory phenomena

86 Vitamin C also activates ten-eleven translocation proteins and inhibits pluripotency, eliminating the epigenetic and metabolomic profile of cancer cells

21 Emanating from an imbalanced prooxidant and antioxidant setting, oxidative stress, therefore remains one of the critical components in states of iron deficiency and overload, thus extending its effects on several pathophysiological and chronic complications, including malignancy