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Series A, Biological sciences and medical sciences, 78(1), 7589

The mitochondria are constantly producing deupleted metabolic water from oxygen via oxidative phosphorylation, capturing the deupleted protons that pass through the ATPase pumps from the intermembrane space into the matrix (Seneff and Kyriakopoulos, 2025a)

The images were acquired as stacks of ~40 slices with at 0.75 m z-stack step size intervals using a x40 (NA 1.3) oil immersion objective, which were later combined to obtain a single high-quality image displaying detailed magnification of the cell processes

Additionally, the development of CIPN in rodent models (Table 2) and patients (Table 3) can be prevented by treatment with drugs that enhance mitochondrial function