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Advantage: Sermorelin, based on longer clinical history and suitability for sustained therapy

In the context of HIV/AIDS treatment, lipodystrophy is often associated with metabolic complications, including insulin resistance, dyslipidemia (abnormal levels of fats in the blood), and other cardiovascular risk factors

Sermorelin is a synthetic GHRH analog that stimulates physiologic GH pulses via the pituitary, while Ipamorelin is a selective ghrelin receptor agonist that triggers GH release without affecting other pituitary hormones

Without a clear understanding of hormonal interaction, many users end up doing more harm than good