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(Note that the Css average described above lies between Cmaxss and Cminss, but it is not mathematically equivalent to their arithmetic or geometric mean.) The therapeutic window in a dosing regimen is the range of efficacious, non-toxic plasma concentrations lying between Cmax ss and Cmin ss

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Xu RY, Wang DH, Wang CL, Zhang GC, Wei GY (2018) Improved S-adenosylmethionine and glutathione biosynthesis by heterologous expression of an ATP6 gene in Candida utilis

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