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This process induces the upregulation of AQP4 and causes swelling in the astrocytic end-feet [131]

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Tumor microenvironment has diverse capacities to induce both beneficial and adverse consequences for tumorigenesis and the microenvironment supports metastatic dissemination and colonization at secondary sites

Across biochemical assays, cell culture models, and preclinical animal studies, mechanistic investigations have focused on how BPC-157 interacts with nitric oxide signaling, angiogenic regulation, cytoskeletal remodeling, and epithelial or connective tissue repair processes