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A cohort study from the Nurses Health Study II reinforced these findings, showing that higher total fibre intake was associated with a decreased incidence of GERD symptoms, with the strongest associations observed for fibre from fruits and vegetables, but not from cereals (Reference Samuthpongtorn, Mehta and Ma78)

DOI: 10.1073/pnas.1306182110 Ding, N., Yu, R.T., Subramaniam, N., Sherman, M.H., Wilson, C., Rao, R., Leblanc, M., Coulter, S., He, M., Scott, C., Lau, S.L., Atkins, A.R., Barish, G.D., Gunton, J.E., Liddle, C., Downes, M., Evans, R.M

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For the intracellular metabolomic analysis, cells were quickly washed for three times with PBS to remove contaminations from the media