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Abbreviations CQ: Chloroquine CSCs: Cancer stem cells ER: Estrogen receptor-alpha GPxs: Glutathione peroxidases GSH: Glutathione HCC: Hepatocellular carcinoma hiPSC-MSCs: Mesenchymal stem cells drived from human induced pluripotent stem cells IBC: Inflammatory breast cancer IH: Isorhamnetin LOH: Loss of heterozygosity MnSOD: Manganese superoxide dismutase NAC: N -acetylcysteine PHGPx: Phospholipid GPx ROS: Reactive oxygen species TNBC: Triple-negative breast cancer TFAP2C: Transcription factor AP-2 gamma References Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A

FOXO4-DRI at the heart of longevity research Some cells in the body behave like silent saboteurs

Experimental observations suggest FOXO4-DRI could be relevant for exploring how proteasomal function might be preserved in cardiac tissues, with implications for studying age-associated heart conditions

The combined GLP-1/GIP profile is what gives tirzepatide its edge over semaglutide