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Most patients begin noticing changes around weeks 4-6, with more significant results by weeks 8-12

Who should avoid AHK-Cu Individuals with copper metabolism disorders, specifically Wilson disease or Menkes disease, should not use copper peptides without medical guidance

Since adipose tissue is responsive to endotoxins, bacterial translocation may provide a mechanism whereby the gut microbiome can modulate the adipose metabolome (for review, Kruis et al., 2014 23 ) and consequently exacerbate obesity and its related comorbidities

Its also worth noting that rotating between multiple SQ sites is more comfortable than rotating IM sites