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Targeting endoplasmic reticulum stress and autophagy as therapeutic approaches for neurological diseases

doi: 10.3390/ma14123332 227 TangMTaghibiglouC

Animal experiments have used iPS cells as a cell source and induced differentiation into notochordal cells (Sheyn et al., 2019), nucleus pulposus-like cells (Zhang et al., 2020), or cartilaginous tissue (Kamatani et al., 2022)

It has been suggested that the serum levels of toxic AGEs are correlated with the progression of degenerative diseases, such as atherosclerosis or diabetes