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Purity and identity are verified using HPLC, Mass Spectrometry, and UV analysis before release

New England Journal of Medicine, 384(11), 989-1002

Since the inhibition of ASK1 (apoptosis signal-regulation kinase 1) in NLRP3 (NOD-like receptor thermal protein domain associated protein 3) mutant mice can reduce liver fibrosis, hepatocyte death, and liver TNF- expression, it suggests the application prospects of ASK1 inhibitor selonsertib in liver diseases

Furthermore, the analog of -tocopherol, water-soluble vitamin E (Trolox), has been shown to reduce the hepatotoxicity of ATO while enhancing its anti-lymphoma effects