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About this Guide This Clinical Documentation Guide is published by CCO Academy and is intended for credentialed coding, CDI, and clinical documentation professionals

Adverse reactions after a B12 injection may include: A feeling of tightness in the chest Anaphylaxis (difficulty breathing or swallowing) Chest pain Congestive heart failure Heart palpitations Pulmonary edema Rapid heartbeat (tachycardia) Shortness of breath Vascular thrombosis Musculoskeletal Effects Your musculoskeletal system makes up your bones, tendons, cartilage, and connective tissues

Within 48 hours after injection of 100 or 1,000 mcg of Vitamin B12, 50 to 98% of the injected dose may appear in the urine

Foods or supplements high in folic acid, like leafy greens and citrus fruits, could mask deficiencies of vitamin B12