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The key treatment for WD is to promote the excretion of copper and reduce its absorption

They are highly expressed and considered stemness markers for detecting adult and cancer stem cells

However, the barrier for the regeneration of N -phenylthiophthalimide 4g (via TS SN2 ) is up to 32.3 kcal mol 1 , suggesting the turnover of 4g is difficult even under basic condition

The biological role of glutathione and glutathione S-transferases in oxidative stress Numerous studies have shown that in order to avoid prolonged exposure to ROS produced during oxidative stress, the body has a very efficient antioxidant defense system