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In relation to vitamin B 12 , a systematic review of observational studies ( n 7) showed inconsistent results with investigations from developing countries demonstrating reduced cognitive function in children of mothers with deficient B 12 status or with low B 12 intakes whereas there was no evidence of an association between self-reported maternal B 12 intake and offspring cognitive performance in the cohorts from developed countries (Reference Veena, Gale and Krishnaveni119)