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Description

Biochimica et Biophysica Acta, 1863(8), 20442053

To exclude that the detected inhibition of NS3-NS5 interaction by the active compounds might be due to a non-specific mechanism of colloidal formation, their inhibitory activities were also tested in the presence of Triton X-100, a well-characterized non-ionic detergent that reverses and prevents aggregates of small molecules (McGovern et al., 2003)