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Emerging players at the intersection of chondrocyte loss of maturational arrest, oxidative stress, senescence and low-grade inflammation in osteoarthritis

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Previous literature [26] reported a faster rate of atrophy in MS patients (0.5-1.35% per year) compared to age-matched HCs (0.1-0.3% per year), which is consistent with our annual PBVC value of -0.4 and -0.55 for RRMS cohort and -0.19 for HCs group over 2 years